1994 • $69.00 • Student $45.00 • 274 pp • hardback
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Focusing on specific inherited disorders such as cystic fibrosis, Duchenne and Becker muscular dystrophy, and the fragile X syndrome, Heim and Silverman survey clinical applications of new recombinant DNA technologies that allow for the diagnosis at the DNA level of these and other human diseases. This book emphasizes both general applications and specific diagnostic techniques, including new techniques such as localized in situ amplification of nucleic acids on microscope slides.